Work place: School of Physics, Sambalpur University, Odisha, India
Research Interests: Physics, Computational Physics
Gana Nath Dash received his PhD from the Sambalpur University, India in 1992. He is currently a Professor in the Department of Physics, Sambalpur University, India. He has published more than 135 papers in journals of repute and proceedings of conferences. He is a senior member of IEEE and a Fellow and Life member of IETE. His research interests include studies on microwave and other devices. Recently, he has developed interest in ANN and signal-processing applications.
DOI: https://doi.org/10.5815/ijigsp.2012.07.05, Pub. Date: 28 Jul. 2012
Discrimination of protein coding regions called exons from noncoding regions called introns or junk DNA in eukaryotic cell is a computationally intensive task. But the dimension of the DNA string is huge; hence it requires large computation time. Further the DNA sequences are inherently random and have vast redundancy, hidden regularities, long repeats and complementary palindromes and therefore cannot be compressed efficiently. The objective of this study is to present an integrated signal processing algorithm that considerably reduces the computational load by compressing the DNA sequence effectively and aids the problem of searching for coding regions in DNA sequences. The presented algorithm is based on the Discrete Wavelet Transform (DWT), a very fast and effective method used for data compression and followed by comb filter for effective prediction of protein coding period-3 regions in DNA sequences. This algorithm is validated using standard dataset such as HMR195, Burset and Guigo and KEGG.[...] Read more.
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