Work place: Chemical Engineering, Vikash College of Engineering for Women, Bargarh, Odisha, India.
Research Interests: Earth Sciences, Earth & Environmental Sciences, Bioinformatics
Madhab Ranjan Panigrahi has received his Ph.D, M.Tech and B.Tech in Chemical Engg from IIT Kharagpur, IIT Madras and NIT Rourkela, India respectively. He has hand on experience of research as a senior scientist in Regional Research Laboratory, Bhubaneswar, Odisha, India. Currently he is the principal of Vikash College of Engg for Women, Bargarh, Odisha, India. His research area includes hydrodynamics, environmental science, energy management and herbal bioinformatics.
DOI: https://doi.org/10.5815/ijigsp.2012.07.05, Pub. Date: 28 Jul. 2012
Discrimination of protein coding regions called exons from noncoding regions called introns or junk DNA in eukaryotic cell is a computationally intensive task. But the dimension of the DNA string is huge; hence it requires large computation time. Further the DNA sequences are inherently random and have vast redundancy, hidden regularities, long repeats and complementary palindromes and therefore cannot be compressed efficiently. The objective of this study is to present an integrated signal processing algorithm that considerably reduces the computational load by compressing the DNA sequence effectively and aids the problem of searching for coding regions in DNA sequences. The presented algorithm is based on the Discrete Wavelet Transform (DWT), a very fast and effective method used for data compression and followed by comb filter for effective prediction of protein coding period-3 regions in DNA sequences. This algorithm is validated using standard dataset such as HMR195, Burset and Guigo and KEGG.[...] Read more.
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