Oleksandr Korchomnyi

Work place: Military-Diplomatic Academy named after Eugene Bereznyak, Kyiv, Ukraine



Research Interests: Data Mining, Database Management System, Mathematics of Computing, Theory of Computation, Models of Computation


Oleksandr Korchomnyi is Candidate of Technical Sciences (PhD) since 2008. From 2010, he is an Associate Professor of Military-Diplomatic Academy named after Eugene Bereznyak, Kyiv, Ukraine. He has about 38 scientific publications. His research interests are data mining of complex data, management of complex dynamic objects.

Author Articles
An Effectiveness Evaluation of Information Technology of Gene Expression Profiles Processing for Gene Networks Reconstruction

By Sergii Babichev Maksym Korobchynskyi Serhii Mieshkov Oleksandr Korchomnyi

DOI: https://doi.org/10.5815/ijisa.2018.07.01, Pub. Date: 8 Jul. 2018

The paper presents the research results concerning an effectiveness evaluation of information technology of gene expression profiles processing for purpose of gene regulatory networks reconstruction. The information technology is presented as a structural block-chart of step-by-step stages of the studied data processing. The DNA microchips of patients, who were investigated on different types of cancer, were used as experimental data. The optimal parameters of data processing algorithm at appropriate stage of this process implementation by quantity criteria of data processing quality were determined during simulation. Validation of the reconstructed gene networks was performed with the use of ROC-analysis by comparison of character of genes interconnection in both the basic network and networks reconstructed based on the obtained biclusters.

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