Work place: Military-Diplomatic Academy named after Eugene Bereznyak, Kyiv, Ukraine
Research Interests: Information Systems, Data Mining, Database Management System, Data Structures and Algorithms, Theory of Computation, Models of Computation
Serhii Mieshkov is Candidate of Technical Sciences (PhD) since 2014. From 2016, he is a First vice-rector of Military-Diplomatic Academy named after Eugene Bereznyak, Kyiv, Ukraine. He has about 56 scientific publications. His research interests are information technology, management of complex dynamic objects, data mining of complex data.
DOI: https://doi.org/10.5815/ijisa.2018.07.01, Pub. Date: 8 Jul. 2018
The paper presents the research results concerning an effectiveness evaluation of information technology of gene expression profiles processing for purpose of gene regulatory networks reconstruction. The information technology is presented as a structural block-chart of step-by-step stages of the studied data processing. The DNA microchips of patients, who were investigated on different types of cancer, were used as experimental data. The optimal parameters of data processing algorithm at appropriate stage of this process implementation by quantity criteria of data processing quality were determined during simulation. Validation of the reconstructed gene networks was performed with the use of ROC-analysis by comparison of character of genes interconnection in both the basic network and networks reconstructed based on the obtained biclusters.[...] Read more.
Subscribe to receive issue release notifications and newsletters from MECS Press journals