Work place: Engineering College of Armed Police Force, 710086, Xi’an, China
Research Interests: Medical Informatics, Models of Computation
Yueping Peng was born in on 10 February, 1974. he got the Ph.D degree in Biomedical Engineering of Xi’an Jiaotong University in 2010. He received the B.S. degree in Communication Engineering and M.S. degree in Information Engineering, both from Engineering College of Armed Police Force, in 1997 and 2003, respectively. Now he is a member of China Association of Rehabilitation of Disabled Persons and of China Association of Biomedical Engineering. He is a professor, communication engineering department, Engineering College of Armed Police Force. He has pubilished over sixty papers in some science journals and joined thirteen research projects. His research interests are in the dynamic mechanism of neurons’ injury and rehabilitation, the signal and information processing, and the neurodynamics and Its application.
DOI: https://doi.org/10.5815/ijigsp.2011.04.05, Pub. Date: 8 Jun. 2011
The hippocampal CA1 pyramid neuron has plenty of discharge actions. The one-compartment model of CA1 pyramid neuron developed by David is a nine-dimension complex dynamic model. In the thesis, the currents related to the nine-dimension complex model are analyzed and classified by the model’s reduction theory and methods based on neurodynamics, and four minimal models are gotten: (INa+IKdr)-minimal model, (INa+IM)-minimal model, (INa+ICa+Iy)-minimal model, and (INa+ICa+IsAHP)-minimal model. These minimal models have plenty of dynamic actions, and under the current’s stimulation, they can all generate regular discharge and have period discharge pattern, bursting pattern, the chaos discharge pattern, and so on. Compared with the initial nine-dimension complex model, these minimal models’ dimension are much reduced, and are more convenient to numerical simulation, calculating, and analyzing. In addition, these minimal models provide a simpler and flexible method to discuss the specific currents’ dynamic characteristics and functions of the initial nine-dimension complex model by the theory of neurodynamics.[...] Read more.
DOI: https://doi.org/10.5815/ijieeb.2011.01.06, Pub. Date: 8 Feb. 2011
The hippocampal CA1 pyramid neuron has plenty of discharge actions. In the thesis, the dynamic characteristics of the hippocampal neuron model are analyzed and discussed by the neurodynamic theory and methods. Under a certain amplitude current’s stimulation, the change of gNa(the maximum conductance of the transient sodium channel) and gKdr (the maximum conductance of the delay rectification potassium channel) can cause different dynamic characteristics of the neuron model. The transient Na+ current(INa ) caused by gNa is indispensable in the discharge’s formation process of the model. The model can generate the discharge process only when gNa reaches a certain threshold. In the discharge process of the neuron model, gNa’s changing affects little and the ISIs approximate to a straight line. The delay rectification K+ current(Ikdr) caused by gKdr isn’t indispensable in the discharge’s formation process of the model. But gKdr’s changing affects much in the discharge process of the neuron model. With gKdr’s changing, the neuron model undergoes different dynamic bifurcation process, and has plenty of discharge patterns such as the chaos, period, and so on. This investigation is helpful to know and investigate the dynamic characteristics and the bifurcation mechanism of the hippocampal neuron; and it provides a certain theory assist to investigate the neural diseases such as the Alzheimer disease by neurodynamics.[...] Read more.
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